This project report talks about the differential specificity related to Protein Kinases and the various applications of it. We have discussed about Basophilic protein kinases, Proline directed protein kinases, Inhibitors of protein kinases, Protein and peptide site directed inhibitors, Bi-substrate inhibitors, etc.
We have done this projects to get a deep understanding of how chaperones communicate with unstable, aggregation prone, misfolded proteins linked to human disease. Molecular chaperones are proteins which act as agents that aid other proteins to fold accurately. The projects discusses about Protein folding, Genetic mutations, Protein misfolding, Transthyretin (TTR), Molecular chaperones, Apoptosis, Caspases Methods, Cloning, mutagenesis, etc.
Thera are a couple of important human pathogens in the family of Chlamydiaceae. Distinct serovars of Chlamydia trachomatis lead to sexually-transmitted disease and eye infections as opposed to C. pneumoniae (TWAR) is a typical cause of community-acquired respiratory infection. Chlamydia has a type III secretion system essential for delivery of effector proteins in to the host for host-cell interactions.
The primary purpose of this research project is to study the risk of artemisinin in early pregnancy employing a qualitative research technique. Artemisinin-Based Combination Therapy (ACT) is considered the most effective and recommended antimalarial treatment presently. Some other topics discussed are: artemisia efficiency in pregnancy, artemisinin control in pregnancy, etc.
The main goal in this project report was to see if good quality DNA could possibly be extracted from ingredients utilized in beer brewing like barley, malt and hop . Good quality DNA is critical in DNA fingerprinting methods that could be utilized for detection of ingredients. To be able to analyze the DNA quality right after extraction we applied 3 distinct methods.
Considering the fact that plants are unable to avoid their predators by walking, they use some other defense systems, like induction or repression of defense genes. A test carried out with barley attacked by the bird cherry-oat aphid (Rhopalosiphum padi), resulted in
The primary aim of this thesis is to research Gelsolin Family Proteins. Gelsolin is undoubtedly an actin-binding protein which is an important regulator of actin filament assembly and disassembly. The actin cytoskeleton serves as a advanced structure that carries out a multitude of cellular functions. Gelsolin is probably the most powerful members of the actin-severing gelsolin/villin superfamily. Some topics discussed in this project are: Actin dynamics, Actin-binding proteins, Actin dynamics at the cell membrane, Cytoskeleton and pathology, etc.
This project is about the mechanisms associated with amyloid induced cytotoxicity. Amyloidoses consist of several diseases where normal or mutated protein precipitates into amyloid fibrils. Dysfunction of organs and toxicity to nervous tissue is triggered by the deposition of fibrils. Presently 24
This project report is on Haptoglobin (Hp), which is a serum protein recognized for its capability to form a tight complex with hemoglobin (Hb) and thus suppressing the oxidative activity of Hb. Some topics studied in this project are: Protein secretion, Glycosylation, Gene duplications, Haptoglobin, Biosynthesis, etc.
The Murine Pneumotropic Virus (MPtV), contrary to MurinePolyomavirus (MPyV), seems to be non-tumourigenic in its natural host. Rather, MPtV leads to severe pneumonia and it can also function as a model in research of polyomavirus-induced sickness. When we tested it initially, MPtV