Hormone replacement therapy project report

In this report the main objective was to study medication utilization and compliance to recommended therapy in a female population in central Sweden. To study usage of hormone replacement therapy (HRT) in this population and to assess how HRT users compare to non-users with regards to symptom reporting, overall health and other variables. To judge symptom prevalence adjusted for possible symptom affecting variables….

We will employ a cross-sectional postal questionnaire. A questionnaire was given to a random sample of 4,200 women aged 35-64, of whom 2,991 responded (71.2%). The list of questions contained questions about psycho-socio-economic background, quality of life, self-reported health, height and weight, climacteric symptom prevalence, and menopausal status and symptoms. Additionally, it consisted questions about medication prescribed over the past year…..

40% used prescribed medication and 12% took four drugs or more. Age, educational level, self-rated health, and BMI continued to be considerably associated to drug use in multivariate analysis. Adherence ranged from 15%-98% determined by age, a scheduled check-up, perceived value of medication, concern about medication, taking cardiovascular and respiratory disease drugs. The maximum compliance was found for hormonal medication the lowest for musculoskeletal medication. Hormone replacement therapy¬†HRT was used by 15% of the women. 13 % used other symptom relieving therapy. HRT users reported higher score of vasomotor symptoms, except for sweating during the daytime….

Age, health status, educational level and body mass index (BMI) seem to affect drug use. Compliance with therapy is highest among elderly ladies who consider their medication important and have a scheduled check-up…..


Menopause and climacteric complaints
Aims of the study
Study population and Methods
Statistical considerations
Reported current use of prescription medications and some of its determinants (Paper 1)
Characteristics of the study population
Diseases under treatment and use of drugs
Factors correlated to the use of drugs
Factors associated with adherence to drug therapy (Paper 2)
Possible determinants of adherence
Hormone replacement therapy and symptom reporting in menopausal
women (Paper 3)
Menopausal state and symptoms
Hormone replacement therapy and symptom reporting
Age-specific symptom prevalence (Paper 4)
Prevalence patterns
Current use of prescription drugs and some of its determinants
Adherence to drug therapy………..

Hormone replacement therapy (HRT)

Source: Uppsala University Library

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