breast cancer

Stem cells have the capacity for both self renewal, and to form all cell types in the body. Interestingly, so called neural stem cells (NSCs) are found in the adult human brain, which is of significance both out of a developmental perspective and from a clinical point of view. At the present moment, the regulation of neural stem cell (NSC) proliferation and fate determination is not completely understood.The overall aim of this thesis was to study the mechanisms that regulate ...

Factors related to the posttraumatic growth experiences of spouses of breast cancer survivors, including optimism, self-mastery, coping styles, marital satisfaction, and social support, were examined. Results indicated the existence of a positive relationship between posttraumatic growth and optimism, social support, and several coping styles, including problem-solving, reframing, seeking support, and New Directions. Posttraumatic growth was negatively related to avoidance coping... Contents Chapter One: Introduction Chapter Two: Review of the Literature Posttraumatic Growth: Coping Process of Outcome ? Posttraumatic Growth: Theory and Contributing Factors A Model of ...

The experience of daughters of women with breast cancer has been virtually ignored in the literature. The few studies that do exist on this population have focused on prevention or daughters' short-term psychological concerns. The current study examined the biopsychosocial variables that affected the reactions of 142 adult daughters of women with breast cancer. Data was collected via a web-based survey and analyzed using cluster and correlational analyses... Contents Chapter I: Introduction Chapter II: Review of the Literature Biology of Breast Cancer Absolute Risk Factors Lifestyle ...

A large proportion of breast cancer patients are treated with radiotherapy. Ionising radiation induces different DNA damages, of which double-strand breaks are the most severe. They are mainly repaired by homologous recombination or non-homologous end-joining. Different protein complexes have central roles in these repair processes. In addition to the ability to repair DNA damage, cellular radiosensitivity is also affected by mitogenic signals that stimulate survival and inhibit apoptosis... Contents Introduction Importance Breast cancer Risk factors Prognosis versus prediction of treatment outcome Breast cancer tumour biology Tumour suppressors versus ...