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Type 1 diabetes (T1D) is due to a selective loss of the insulin producing β-cells. However, the process responsible for this loss is still unknown. There is accumulating evidence that enteroviruses (EVs) are involved in T1D. In addition to direct virus-induced cytolysis,
Poly(A) polymerase (PAP) is the enzyme catalyzing the synthesis of the adenine tail to the 3’-end of mRNA. This A-tail is present on the majority of the primary RNA transcripts of protein-coding genes, and is important for mRNA stability, export to the
The positron emitting radionuclide 68Ga (T1/2 = 68 min) might become of practical interest for clinical positron emission tomography (PET). The metallic cation, 68Ga(III), is suitable for complexation with chelators, either naked or conjugated with biological macromolecules. Such labelling procedures require pure
The phylum Priapulida is a small group of marine worms that is allied with the nematodes, kinorhynchs, loriciferans and nematomorphs in a clade called the Cycloneuralia or Introverta. Together with the arthropods they are generally considered to comprise the Ecdysozoa, a clade
This dissertation deals with aspects of axiomatization, intuition and visualization in the history of mathematics. Particular focus is put on the end of the 19th century, before David Hilbert’s (1862–1943) work on the axiomatization of Euclidean geometry. The thesis consists of three
In this thesis we have performed core-electron spectroscopy studies of gas phase molecular systems starting with smaller diatomic, continuing with triatomic and extending our research to more complex polyatomic ones. We can subdivide the results presented here into two categories: the first
Thermal spraying is the name of a large group of coating deposition techniques used to deposit thick layers for a variety of applications. The principle is to melt the material, and rapidly propel the droplets towards a substrate where they flatten and
Cyclotides are a family of small and macrocyclic proteins that have been found in Violacaee and Rubiaceae plant species. These proteins contain a cystine knot: two disulfides bonds together with their connecting peptide backbone form an embedded ring which is penetrated by
A community food system (CFS) can assist a community in satisfying human needs while also working toward a principle-based understanding of sustainability. Utilizing a whole-systems perspective and the Framework for Strategic Sustainable Development, we identify generic satisfiers of human needs (as defined
The aim with this thesis is to investigate the industrial buying behavior in Scandinavian pulp and paper mills. The focus in this industry, as well as in other asset-intensive industries, has shifted from buying and selling large machine installations to a more