Thera are a couple of important human pathogens in the family of Chlamydiaceae. Distinct serovars of Chlamydia trachomatis lead to sexually-transmitted disease and eye infections as opposed to C. pneumoniae (TWAR) is a typical cause of community-acquired respiratory infection. Chlamydia has a type III secretion system essential for delivery of effector proteins in to the host for host-cell interactions.
Comparative reports of bacterial genomics, now counting in the 100s, produce enormous amounts of information. To be able to support an organized and successful strategy to genomic analyses, a database powered program with graphic visualization of genomic qualities was created – GenComp. The application was employed on studies of obligate intracellular bacteria.