Celiac disease (CD) is an inflammatory small-bowel enteropathy caused by a permanent intolerance to wheat gluten and related proteins in rye and barley. Even though the disease originate from the small intestine the clinical symptoms varies in affected individuals and are often different in small children…
Contents
INTRODUCTION
CELIAC DISEASE
Historic background
Clinical features
Epidemiology
Genetic predisposition
Diagnostic procedure
Associated diseases
Treatment
Gluten and its interplay with tissue transglutaminase
The human intestine
Intestinal microbiota
THE IMMUNE SYSTEM
INNATE IMMUNITY
Mucins
Antimicrobial peptides
The carcinoembryonic antigen family
Lectins
ADAPTIVE IMMUNITY
Major histocompatibility complex (MHC)
Cytokines
T CELL MATURATION
Intrathymic T cell maturation
Extrathymic TCR gene rearrangement
Gut Associated Lymphoid Tissue (GALT)
Intra epithelial lyphocytes….
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Author: Forsberg, Göte
Source: Umea University
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Keywords: Project Reports, Dissertation, Thesis