Thoracic Aortic Surgery: Epidemiology, Outcomes, and Prevention of Cerebral Complications

The mortality of thoracic aortic diseases (mainly aneurysms and dissections) is high, even with surgical treatment. Epidemiology and long-term outcomes are incompletely investigated. Stroke is a major complication contributing to mortality, morbidity, and possibly to reduced quality of life.
Study I Increasing incidence of thoracic aortic diseases 1987 – 2002 was demonstrated (n=14229). Annual number of operations increased eight-fold. Overall long-time survival was 92%, 77%, and 57% at 1, 5, and 10 years. Risk of operative and long-term mortality was reduced across time…

Contents

Introduction
Diagnostic and procedural codes
International classification of diseases
Nomesco Classification of surgical procedures
National health registers
The Hospital Discharge Register
The Cause of Death Register
The Swedish heart surgery register
Epidemiology
Natural history
Surgical treatment: rationale and indications
Type A aortic dissection
Type B aortic dissection
Thoracic and thoracoabdominal aortic aneurysms
Surgical treatment: outcomes
Short-term results
Long-term results
Surgical treatment: complications
Cerebral complications
Prevention of cerebral complications
Cannulation site
Cerebral monitoring
Cerebral perfusion strategies
Hypothermic circulatory arrest
Retrograde cerebral perfusion
Selective antegrade cerebral perfusion
Comparing HCA, RCP, and SACP
Quality of life
The short-form 36 (SF-36) self-rated health questionnaire
Quality of life in cardiac surgical patients
Aims of the thesis

Author: Olsson, Christian

Source: Uppsala University Library

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