Chicken Genomics – Linkage and QTL mapping

This thesis presents results from genetic studies conducted in the chicken (Gallus gallus). The domestication of chicken is believed to have been initiated approximately 7,000 – 9,000 years ago in Southeast Asia. Since that time, selective breeding has altered the appearance of the wild ancestor, creating highly specialized chicken lines developed for egg and meat production.The first part of this thesis describes a detailed genetic analysis conducted on an F2 intercross between two phenotypically diverse chicken lines. The two parental lines used in this experiment originated from the same base population and have been developed by divergent selection for juvenile body-weight. Selection during forty generations has resulted in an eight-fold difference in body-weight between the High-Weight Selected (HWS) and Low-Weight Selected (LWS) line. In an attempt to identify the genetic factors differentiating the two lines, a large intercross population was bred to map Quantitative Trait Loci (QTL)…


The evolution of the domestic chicken
The chicken genome
Mendelian genetics
Linkage analysis and construction of linkage maps
Quantitative genetics
QTL mapping
Aims of the thesis
Present investigations
Construction and analysis of genetic linkage maps in chicken (Paper II and III)
Results and Discussion
Future perspective
Genetic analysis of two extreme selection lines – QTL mapping (Paper I and IV)
Results and Discussion
Future perspective

Author: Wahlberg, Per

Source: Uppsala University Library

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