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Signals and Noise in Complex Biological Systems

In every living cell, millions of different types of molecules constantly interact and react chemically in a complex system that can adapt to fluctuating environments and extreme conditions, living to survive and reproduce itself. The information required to produce these components is stored in the genome, which is copied in each cell division and transferred and mixed with another genome from parent to child.

Solubility and Surface Complexation Studies of Apatites

Apatites are a diverse class of phosphate minerals that are important in a great variety of natural and industrial processes. They are, for example, used as raw material in fertiliser production and in the remediation of metal-contaminated soils. Hydroxyapatite Ca5(PO4)3OH, (HAP) and fluorapatite Ca5(PO4)3F, (FAP) are similar to the biological apatite that is the main constituent of mammalian bone and teeth, and they are therefore promising materials for artificial bone and tooth implants.

Apoptosis Regulation via the Mitochondrial Pathway: Membrane Response upon Apoptotic Stimuli

The aim of this thesis (Apoptosis Regulation via the Mitochondrial Pathway: Membrane Response upon Apoptotic Stimuli) was the investigation of the mitochondrial response mechanisms upon apoptotic stimuli. The specific objectives were the biophysical characterization of membrane dynamics and the specific roles of

Fluorescence studies of complex systems: organisation of biomolecules

The homo and hetero dimerisation of two spectroscopically different chromophores were studied, namely: 4,4-difluoro-4-bora-3a,4a-diazas-indacene (g-BODIPY) and its 5-styryl-derivative (r-BODIPY). Various spectroscopic properties of the r-BODIPY in different common solvents were determined. It was shown that g- and r-BODIPY in the ground state

Synthesis, properties and applications of chalcogen-containing antioxidants

In the first part, the preparation and properties of chalcogen-containing vitamin E analogues are described. The sulfur compound 3,3,4,6,7-pentamethyl-2,3-dihydrobenzo[b]thiophene-5-ol was prepared by two different routes using ionic… Contents 1. INTRODUCTION 1.1 Oxygen in biological and polymeric systems 1.1.1 General introduction 1.1.2 Mechanism